Publications
Patents:
- Device for Dielectrophoretic Manipulation of Particles
MP Hughes, KF Hoettges, SL Ogin, R Wattingham; Filed 28th February 2003
Journal papers:
- A Dielectrophoresis-Activated Multiwell Plate for Label-Free High-Throughput Drug Assessment
K.F. Hoettges, Y. Hubner, L.M. Broche, S.L. Ogin, G.E.N. Kass, M.P, Hughes,
Analytical Chemistry 2008 80 2063-2068; DOI: 10.1021/ac702083g
- A Rapid determination of antibiotic resistance in E. coli using dielectrophoresis,
K.F. Hoettges, J.W. Dale, M.P. Hughes,
PHYSICS IN MEDICINE AND BIOLOGY 2007 52 6001-6010
- A Dielectrophoresis for drug discovery and cell analysis: novel electrodes for high-throughput screening;
M.P. Hughes, K.F. Hoettges;
Biophysical Journal 200588 (1): 172A-172A Part 2 Suppl
- A Dielectrophoresis as a Screening Tool - Label-free Electrophysiology Assays;
K.F. Hoettges, Y. Hubner, G.E.N. Kass, S.L. Ogin, M.P.Hughes;
Screening - trends in Drug discovery 3/2005, 28-20
- A In situ and real time determination of metallic and semiconducting single-walled carbon nanotubes in suspension via dielectrophoresis ,
N. Mureau, E. Mendoza, S. R. P. Silva, K.F. Hoettges, and M.P. Hughes;
Appl. Phys. Lett. 2006 88, 243109
- Differences in the biophysical properties of membrane and cytoplasm of apoptotic cells revealed using dielectrophoresis.
FH Labeed, HM Coley, H Thomas, MP Hughes
Biochimica et Biophysica Acta 1760 (2006) 922-929
- Parallel measurements of drug actions on Erythrocytes by dielectrophoresis, using a novel 3-dimensional electrode design
Y Hubner, KF Hoettges, GEN Kass, SL Ogin, MP Hughes
IEE Proceedings on Bionanotechnology 2005 4 21-25
- A 3D dielectrophoretic separator
HO Fatoyinbo, D Kamchis, R Whattingham, SL Ogin, MP Hughes
IEEE Transactions on Biomedical Engineering 2005 52 1347-1349
- Extraction of dielectric properties for multiple populations from dielectrophoretic collection spectrum data
L Broche, FH Labeed, MP Hughes
Physics in Medicine and Biology 2005 50 2267-2274
- Water quality test based on dielectrophoretic measurements of fresh water algae Selenastrum capricornutum
Y Hubner, KF Hoettges, MP Hughes
Journal of Environmental Monitoring 2003 5 861-864
- Assessment of multidrug resistance reversal using dielectrophoresis and flow cytometry
FH Labeed, HM Coley, H Thomas, MP Hughes
Biophysical Journal 2003 85 2028-2034
- Dielectrophoretic assay of bacterial resistance to antibiotics
J Johari, Y Hubner, J Hull, JW Dale, MP Hughes
Physics in Medicine and Biology 2003 48 N193-N196
- Dielectrophoretic analysis of changes in cytoplasmic ion levels due to ion channel blocker action reveals underlying differences between drug-sensitive and multidrug-resistant leukaemic cells
L Duncan, H Shelmerdine, M P Hughes, H M Coley, Y Hubner, F H Labeed;
Phys. Med. Biol. 53 (2008) N1-N7
- Early detection of oral cancer? Is dielectrophoresis the answer?
L. M. Broche, N. Bhadal, M.P. Lewis, S. Porter, M.P. Hughes, F.H. Labeed;
Oral Oncology (2007) 43, 199- 203
- Biophysical characterization of MDR breast cancer cell lines reveals the cytoplasm is critical in determining drug sensitivity
H.M. Coley, F.H. Labeed, H. Thomas, M.P. Hughes;
Biochimica et Biophysica Acta 1770 (2007) 601-608
- Rapid assessment of early biophysical changes in K562 cells during apoptosis determined using deielctrophoresis
S. Chin, M.P. Hughes, H.M. Coley, F.LH. Labeed;
Int. J. Nanomed. 3 (2006) 333-337
Conference papers:
- Dielectric analysis of cancerous versus normal oral cells using dielectrophoresis shows differences in the membrane and cytoplasm.
FH Labeed, LM Broche, N Bhadal, MP Lewis, HM Coley, MP Hughes,
96th Annual Meeting of the American Association for Cancer research (Anaheim, USA, 2005)
- Dielectrophoresis for drug discovery and cell analysis; novel electrodes for high-throughput screening
MP Hughes, KF Hoettges,
49th Annual Meeting of the Biophysical Society (Long Beach, USA 2005)
- Finite Element Modelling of a 3-Dimensional Dielectrophoretic Flow Separator Device for Optimal Bioprocessing Conditions
HO Fatoyinbo, MP Hughes,
26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (San Francisco, USA, 2004)
- Rapid assay of apoptotic progress of mixed populations by dielectrophoresis
FH Labeed, MP Hughes, H Thomas, HM Coley,
95th Annual Meeting of the American Association for Cancer research (Orlando, USA, 2004)
- Dielectrophoresis for Assessment of Drug Action
MP Hughes, KF Hoettges, FH Labeed, HO Fatoyinbo, Y Hubner,
15th International Bioanalytical Forum (Guildford, UK, 2003)
- Dielectrophoretic assessment reveals major differences in the biophysical properties of the membrane and cytoplasm of MDR versus parental lines
FH Labeed, MP Hughes, H Thomas, HM Coley,
94th Annual Meeting of the American Association for Cancer research (Washington DC, USA, 2003)
- Assessment of modulator action on drug- resistant and sensitive cancer cells using dielectrophoretic methods
FH Labeed, MP Hughes, P Charlton, HM Coley,
British Association for Cancer Research Annual Meeting (Glasgow 2002)
- Dielectrophoretic assessment of modulator action on drug-resistant and sensitive cancer cells
FH Labeed, MP Hughes, HM Coley,
Electromagnetic methods in pharmacy and medicine (Canterbury, 2002)
Books
- Nanoelectromechanics in Engineering and biology MP Hughes, CRC Press 2002
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